Abbreviations ASC, apoptosis associated speck like protein; BMDM, bone marrow derived macrophage; CAPS, cryopyrin associated periodic syndrome; Casp1, caspase 1; CPPD, calcium pyrophosphate dihydrate; CINCA, Chronic Infantile Neurological, Cutaneous, and Articular Syndrome; Cre ERT2, Cre recombinase estrogen receptor fusion protein; CreT, Cre ERT2 fusion gene; CRID, Cytokine Release Inhibitory Drug; DAMP, danger associated molecular pattern; ER Hoxb8, estrogen regulated homeobox protein Hox B8; FCAS, Familial Cold Autoinflammatory Syndrome; GSDMD, gasdermin D; GSTO1, Glutathione S transferase omega 1; HD, helical domain; HEK, human embryonic kidney; HPMA, N 2 hydroxypropyl methacrylamide; IC 50, half maximal inhibitory concentration; IL, interleukin; iMac, ER Hoxb8 immortalized macrophages; IP, intraperitoneal; LPS, lipopolysaccharides; LRR, leucine rich repeat; MEFV, Mediterranean fever; MSU, monosodium urate; MWS, Muckle Wells syndrome; NACHT, NAIP, CIITA, HET E, and TP1; NAFLD, nonalcoholic fatty liver disease; NASH, nonalcoholic steatohepatitis; NBD, nucleotide binding domain; NEK7, never in mitosis gene a related kinase 7; NF ОєB, nuclear factor ОєB; NLR, NBD and LRR containing; Nlrc4, NLR family, caspase recruitment domain containing 4; NLRP3, NLR family, pyrin domain containing 3; NOD, nucleotide binding oligomerization domain; NOMID, Neonatal Onset Multisystem Inflammatory Disease; ns, not significant; PAL, photoaffinity labeling; PAMP, pathogen associated molecular pattern; Pam3CSK4, N palmitoyl S dipalmitoylglyceryl Cys Ser Lys 4; PBMC, peripheral blood mononuclear cell; PP1Cb, protein phosphatase 1 catalytic subunit ОІ isoform; PYD, Pyrin domain; TAMRA, 5 carboxytetramethylrhodamine; WHD, winged helix domain <a href=http://clomid.mom/>side effects of clomid in woman</a> |
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